TMPRSS3

Across TCGA patient cohorts, TMPRSS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,452 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMPRSS3-associated proteins across cancer lineages are FMN1, GMDS, and GSDMB. Each is linked with TMPRSS3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMPRSS3-to-partner and partner-to-TMPRSS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS3 versus FMN1 in UCEC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS3→partner) and Y-score (partner→TMPRSS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FMN1 →	+0.396	+0.675	<.001	.005	3	5
LUAD	GMDS →	+0.669	+1.354	<.001	<.001	3	5
LSCC	GSDMB →	+1.251	+0.921	<.001	<.001	3	5
HNSC	HID1 →	+0.430	+0.492	<.001	<.001	3	5
HNSC	PSMB8 →	+0.273	+0.445	<.001	.008	3	5
BRCA	ANXA3 →	+0.857	+1.736	.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,452 associations by consensus.

TMPRSS3 vs FMN1 — UCEC

Explore this scatter interactively →