TMPRSS13

Across TCGA patient cohorts, TMPRSS13 protein abundance is significantly associated with the RNA expression of many other genes, with 5,403 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMPRSS13-associated genes across cancer lineages are C1orf174, CCNT2-AS1, and ZNF2. Each is linked with TMPRSS13 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMPRSS13-to-partner and partner-to-TMPRSS13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS13 versus C1orf174 in PDAC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS13→partner) and Y-score (partner→TMPRSS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	C1orf174 →	+0.522	+1.420	.001	.005	2	3
UCEC	CCNT2-AS1 →	+0.816	+1.023	.007	.004	3	2
UCEC	ZNF2 →	+0.716	+1.023	.007	.004	3	2
LSCC	SLC51A →	+0.938	+1.411	.005	.002	3	2
BRCA	SLC39A8 →	-1.888	-1.657	.005	.009	3	2
LSCC	NECTIN4-AS1 →	+1.356	+1.563	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,403 associations by consensus.

TMPRSS13 vs C1orf174 — PDAC

Explore this scatter interactively →