TMPRSS13

Across TCGA cell cohorts, TMPRSS13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,344 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TMPRSS13-associated GO terms across cancer lineages are Response to indole-3-methanol, Regulation of synapse structural plasticity, and Cellular response to indole-3-methanol. Each is linked with TMPRSS13 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMPRSS13-to-partner and partner-to-TMPRSS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by TMPRSS13-low versus TMPRSS13-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS13→partner) and Y-score (partner→TMPRSS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to indole-3-methanol →	+0.249	+2.669	<.001	<.001	3	10
BREAST	Regulation of synapse structural plasticity →	-1.102	-2.723	.001	<.001	3	10
LUNG_NSCLC_LUSC	Cellular response to indole-3-methanol →	+0.229	+1.827	<.001	.004	3	9
LUNG_NSCLC_LUSC	Response to lithium ion →	+0.219	+1.929	<.001	<.001	3	9
OVARY	Serotonin secretion →	+1.424	+1.538	<.001	<.001	3	9
OVARY	Response to molecule of fungal origin →	+1.395	+1.799	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,344 associations by consensus.

Response to indole-3-methanol by TMPRSS13 expression — BREAST

Explore this box plot interactively →