TMPRSS13

Across TCGA cell cohorts, TMPRSS13 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMPRSS13-associated genes across cancer lineages are KRT25, C20orf85, and OR1L4. Each is linked with TMPRSS13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMPRSS13-to-partner and partner-to-TMPRSS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT25 grouped by TMPRSS13-low versus TMPRSS13-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS13→partner) and Y-score (partner→TMPRSS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	KRT25 →	+0.006	+5.285	<.001	.003	3	2
SOFT_TISSUE	C20orf85 →	+0.115	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR1L4 →	+0.072	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR4D6 →	+0.046	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR51L1 →	+0.036	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR51G2 →	+0.036	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

KRT25 by TMPRSS13 expression — STOMACH

Explore this box plot interactively →