Across TCGA patient cohorts, TMPRSS12 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,029 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMPRSS12-associated proteins across cancer lineages are CBX2, SAP30, and SNAP23. Each is linked with TMPRSS12 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMPRSS12-to-partner and partner-to-TMPRSS12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS12→partner) and Y-score (partner→TMPRSS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CBX2 →	+0.976	+0.148	<.001	<.001	3	4
OV	SAP30 →	+0.467	+0.116	.004	.003	3	3
OV	SNAP23 →	-0.320	-0.091	<.001	.007	3	3
LSCC	RBBP4 →	+0.326	+0.214	.001	.009	3	3
LSCC	RBM12 →	+0.195	+0.246	<.001	.006	3	3
LSCC	BCL11A_S432 →	+0.825	+0.241	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,029 associations by consensus.

Exploration

TMPRSS12 survival (RNA) · tumor vs normal (RNA) · all TMPRSS12 data types