Across TCGA cell cohorts, TMPRSS12 RNA expression is significantly associated with the go_rna of many other GO terms, with 255 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMPRSS12-associated GO terms across cancer lineages are Negative regulation of T cell differentiation, Epithelial cell-cell adhesion, and Negative regulation of calcineurin-NFAT signaling cascade. Each is linked with TMPRSS12 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMPRSS12-to-partner and partner-to-TMPRSS12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS12→partner) and Y-score (partner→TMPRSS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of T cell differentiation →	+0.137	+0.078	<.001	.005	3	3
BREAST	Epithelial cell-cell adhesion →	+0.162	+0.074	<.001	.003	3	3
OVARY	Negative regulation of calcineurin-NFAT signaling cascade →	+0.129	+0.023	.002	.005	3	3
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.062	-0.024	<.001	.004	3	3
OVARY	Negative regulation of calcineurin-mediated signaling →	+0.129	+0.023	.002	.005	3	3
OVARY	Response to acid chemical →	+0.056	+0.023	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 255 associations by consensus.

Exploration

TMPRSS12 survival (RNA) · tumor vs normal (RNA) · all TMPRSS12 data types