Across TCGA patient cohorts, TMPRSS11A protein abundance is significantly associated with the RNA expression of many other genes, with 1,250 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMPRSS11A-associated genes across cancer lineages are RHOV, FSD1L, and SGPP1. Each is linked with TMPRSS11A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMPRSS11A-to-partner and partner-to-TMPRSS11A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11A→partner) and Y-score (partner→TMPRSS11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RHOV →	+1.170	+1.033	.006	<.001	3	2
HNSC	FSD1L →	-0.690	-0.711	<.001	<.001	3	2
HNSC	SGPP1 →	-0.954	-0.812	<.001	<.001	3	2
HNSC	ATP13A4 →	+1.484	+0.647	.002	.003	3	2
LSCC	SPECC1 →	-0.828	-1.358	<.001	<.001	3	2
LSCC	RHPN2 →	-1.269	-1.088	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,250 associations by consensus.

Exploration

TMPRSS11A survival (RNA) · tumor vs normal (RNA) · all TMPRSS11A data types