Across TCGA cell cohorts, TMPRSS11A RNA expression is significantly associated with the go_rna of many other GO terms, with 748 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMPRSS11A-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Regulation of stem cell differentiation, and Negative regulation of Wnt signaling pathway. Each is linked with TMPRSS11A in more than 4 cancer types. Because this analysis shows association rather than direction, both TMPRSS11A-to-partner and partner-to-TMPRSS11A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11A→partner) and Y-score (partner→TMPRSS11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Pre-mRNA catabolic process →	+0.060	+0.023	.004	.005	3	5
BLOOD_Leukemia	Regulation of stem cell differentiation →	+0.055	+0.014	.001	.002	3	4
BLOOD_Leukemia	Negative regulation of Wnt signaling pathway →	+0.023	+0.008	.007	.007	3	4
LUNG_NSCLC_LUAD	Regulation of antimicrobial peptide production →	+0.717	+0.025	<.001	.006	3	4
BLOOD_Leukemia	Viral translational termination-reinitiation →	+0.039	+0.008	.002	.007	3	4
BLOOD_Leukemia	Negative regulation of peptide hormone secretion →	-0.097	-0.013	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 748 associations by consensus.

Exploration

TMPRSS11A survival (RNA) · tumor vs normal (RNA) · all TMPRSS11A data types