TMOD3

Across TCGA patient cohorts, TMOD3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,195 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMOD3-associated genes across cancer lineages are ANXA2, CARD6, and TRIP4. Each is linked with TMOD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMOD3-to-partner and partner-to-TMOD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMOD3 versus ANXA2 in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMOD3→partner) and Y-score (partner→TMOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ANXA2 →	+1.051	+0.374	<.001	<.001	3	8
GBM	CARD6 →	+0.856	+0.385	<.001	<.001	3	7
HNSC	TRIP4 →	+0.468	+0.168	<.001	.003	3	6
BRCA	TPM1 →	+0.827	+0.191	<.001	.001	3	6
LUAD	MMP28 →	+1.464	+0.176	<.001	<.001	3	6
LSCC	SCML2 →	-0.955	-0.130	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,195 associations by consensus.

TMOD3 vs ANXA2 — GBM

Explore this scatter interactively →