TMOD1

Across TCGA patient cohorts, TMOD1 mutation is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMOD1-associated genes across cancer lineages are MIR1183, CST8, and OR5P3. Each is linked with TMOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMOD1-to-partner and partner-to-TMOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1183 grouped by TMOD1-low versus TMOD1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMOD1→partner) and Y-score (partner→TMOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR1183 →	+0.365	+5.251	<.001	.006	3	2
COAD	CST8 →	+0.139	+3.843	<.001	<.001	3	1
COAD	OR5P3 →	+0.064	+4.557	<.001	.004	3	1
CESC	RNU6-797P →	+0.238	+5.144	<.001	.003	3	1
CESC	RNU6-1188P →	+0.393	+4.996	<.001	.002	3	1
CESC	RNU6-960P →	+0.205	+5.569	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

MIR1183 by TMOD1 expression — BLCA

Explore this box plot interactively →