TMIGD3

Across TCGA cell cohorts, TMIGD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,245 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMIGD3-associated GO terms across cancer lineages are Apoptotic cell clearance, Lymphocyte migration into lymphoid organs, and Negative regulation of platelet-derived growth factor receptor-beta signaling pathway. Each is linked with TMIGD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMIGD3-to-partner and partner-to-TMIGD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic cell clearance grouped by TMIGD3-low versus TMIGD3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMIGD3→partner) and Y-score (partner→TMIGD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Apoptotic cell clearance →	+0.088	+0.027	.005	.004	3	4
BREAST	Lymphocyte migration into lymphoid organs →	+0.206	+0.025	<.001	.003	3	4
BLOOD_Leukemia	Negative regulation of platelet-derived growth factor receptor-beta signaling pathway →	+0.148	+0.840	<.001	.001	3	4
LARGE_INTESTINE	Positive regulation of collagen metabolic process →	+0.062	+0.027	<.001	.004	3	3
BLOOD_Leukemia	Regulation of neutrophil apoptotic process →	+0.128	+0.680	<.001	<.001	3	3
BLOOD_Leukemia	Positive regulation of neutrophil apoptotic process →	+0.128	+0.680	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,245 associations by consensus.

Apoptotic cell clearance by TMIGD3 expression — LARGE_INTESTINE

Explore this box plot interactively →