TMIGD2

Across TCGA patient cohorts, TMIGD2 protein abundance is significantly associated with the RNA expression of many other genes, with 376 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMIGD2-associated genes across cancer lineages are CRYBB3, POLR2F, and CBY1. Each is linked with TMIGD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMIGD2-to-partner and partner-to-TMIGD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMIGD2 versus CRYBB3 in HNSC, with a Pearson correlation of -0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMIGD2→partner) and Y-score (partner→TMIGD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CRYBB3 →	-1.655	-1.015	<.001	.002	3	1
HNSC	POLR2F →	-1.642	-1.245	.001	<.001	3	1
HNSC	CBY1 →	-0.750	-0.963	.006	.001	3	1
HNSC	SYNGR1 →	-1.005	-0.963	.005	.001	3	1
HNSC	PMM1 →	-1.207	-1.062	<.001	.007	3	1
HNSC	ADNP2 →	-1.194	-1.245	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 376 associations by consensus.

TMIGD2 vs CRYBB3 — HNSC

Explore this scatter interactively →