TMIGD2

Across TCGA cell cohorts, TMIGD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,719 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMIGD2-associated GO terms across cancer lineages are Positive regulation of smooth muscle cell proliferation, D-ribose metabolic process, and DNA replication-dependent chromatin disassembly. Each is linked with TMIGD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMIGD2-to-partner and partner-to-TMIGD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of smooth muscle cell proliferation grouped by TMIGD2-low versus TMIGD2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMIGD2→partner) and Y-score (partner→TMIGD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of smooth muscle cell proliferation →	-0.107	-0.585	<.001	<.001	3	5
SOFT_TISSUE	D-ribose metabolic process →	+0.154	+0.644	<.001	.002	3	5
BONE	DNA replication-dependent chromatin disassembly →	+0.193	+0.399	<.001	.001	3	5
BONE	Stress response to copper ion →	-0.329	-0.624	<.001	.002	3	5
BONE	Detoxification of copper ion →	-0.329	-0.624	<.001	.002	3	5
BONE	Positive regulation of fertilization →	-1.465	-0.452	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,719 associations by consensus.

Positive regulation of smooth muscle cell proliferation by TMIGD2 expression — SOFT_TISSUE

Explore this box plot interactively →