TMIGD1

Across TCGA patient cohorts, TMIGD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,769 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TMIGD1-associated GO terms across cancer lineages are Regulation of DNA-templated transcription initiation, Cellular ketone metabolic process, and Nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with TMIGD1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TMIGD1-to-partner and partner-to-TMIGD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription initiation grouped by TMIGD1-low versus TMIGD1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMIGD1→partner) and Y-score (partner→TMIGD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA-templated transcription initiation →	+0.066	+0.254	<.001	<.001	3	11
STAD	Cellular ketone metabolic process →	+0.038	+0.310	<.001	<.001	3	11
STAD	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.058	+0.302	<.001	<.001	3	10
STAD	Nucleoside triphosphate biosynthetic process →	+0.066	+0.251	<.001	<.001	3	10
STAD	Nucleoside phosphate biosynthetic process →	+0.055	+0.301	<.001	<.001	3	10
ESCA	Protein autoubiquitination →	+0.056	+0.260	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,769 associations by consensus.

Regulation of DNA-templated transcription initiation by TMIGD1 expression — ESCA

Explore this box plot interactively →