TMEM9B-AS1

Across TCGA pan-cancer cohorts, TMEM9B-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TMEM9B-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TMEM9B-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TMEM9B-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCEC show a favorable association.

BRCA, KICH, and KIRC are the cancer types where TMEM9B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	III,IV	0.885	0.691	<.001	66	view →
KICH	DFS	Tertile	All	0.679	1.000	.002	50	view →
KIRC	DFS	Quartile	III,IV	0.548	0.848	.003	41	view →
UCEC	OS	Median	III,IV	0.885	0.767	.008	40	view →
PAAD	DFS	Median	All	0.564	0.400	.003	38	view →
HNSC	DFS	Quartile	IV	0.695	0.404	.001	27	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	24	view →
UCS	DFS	Median	IV	0.909	0.416	.008	18	view →
SKCM	DFS	Median	All	0.786	0.664	.002	17	view →
DLBC	DFS	Median	II,III,IV	1.000	0.189	.003	16	view →
CESC	DFS	Quartile	III,IV	0.532	0.896	.004	14	view →
READ	DFS	Quartile	All	0.913	0.186	.001	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TMEM9B-AS1–BRCA (DFS)

Open the BRCA breakdown →