TMEM99

Across TCGA patient cohorts, TMEM99 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,126 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM99-associated proteins across cancer lineages are ZNF830, FNBP1, and LIG3. Each is linked with TMEM99 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM99-to-partner and partner-to-TMEM99 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM99 versus ZNF830 in LSCC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM99→partner) and Y-score (partner→TMEM99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF830 →	+0.262	+0.565	<.001	<.001	3	6
LSCC	FNBP1 →	-0.361	-0.669	<.001	<.001	3	5
GBM	LIG3 →	+0.379	+0.318	<.001	.002	3	5
BRCA	PLCG2 →	-0.671	-0.828	<.001	<.001	3	5
HNSC	PSME2 →	-0.541	-0.672	<.001	<.001	2	5
LSCC	PTK2B →	-0.421	-0.694	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,126 associations by consensus.

TMEM99 vs ZNF830 — LSCC

Explore this scatter interactively →