TMEM98

Across TCGA cell cohorts, TMEM98 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,059 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TMEM98-associated GO terms across cancer lineages are Aerobic respiration, Respiratory electron transport chain, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with TMEM98 in more than 10 cancer types. Because this analysis shows association rather than direction, both TMEM98-to-partner and partner-to-TMEM98 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by TMEM98-low versus TMEM98-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM98→partner) and Y-score (partner→TMEM98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Aerobic respiration →	+0.100	+1.954	<.001	<.001	3	11
OESOPHAGUS	Respiratory electron transport chain →	+0.131	+2.551	<.001	.001	3	10
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.156	+2.338	<.001	.004	3	10
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.107	+2.030	<.001	<.001	3	10
OESOPHAGUS	Regulation of mRNA catabolic process →	+0.065	+2.244	<.001	.001	3	10
SOFT_TISSUE	Negative regulation of myelination →	+0.318	+2.688	.005	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,059 associations by consensus.

Aerobic respiration by TMEM98 expression — OESOPHAGUS

Explore this box plot interactively →