TMEM97

Across TCGA pan-cancer cohorts, TMEM97 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TMEM97 data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher TMEM97 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TMEM97 expression acts as an unfavorable survival marker.

UCS and COAD are the cancer types where TMEM97 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	All	0.007	0.689	<.001	24	view →
COAD	OS	Median	All	0.172	0.870	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TMEM97–UCS (OS)

Open the UCS breakdown →