TMEM91

Across TCGA cell cohorts, TMEM91 RNA expression is significantly associated with the RNA expression of many other genes, with 10,681 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM91-associated genes across cancer lineages are LENG8, PRSS53, and FAM229A. Each is linked with TMEM91 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM91-to-partner and partner-to-TMEM91 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM91 versus LENG8 in LARGE_INTESTINE, with a Pearson correlation of 0.48.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM91→partner) and Y-score (partner→TMEM91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LENG8 →	+1.422	+0.969	<.001	<.001	3	12
KIDNEY	PRSS53 →	+0.915	+1.417	<.001	.003	3	12
URINARY_TRACT	FAM229A →	+1.337	+1.316	.002	.007	1	14
URINARY_TRACT	ZNF333 →	+1.346	+1.302	.002	.001	1	13
URINARY_TRACT	AGER →	+1.426	+1.670	<.001	<.001	3	11
KIDNEY	PPP1R32 →	+0.928	+2.214	.004	.001	1	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,681 associations by consensus.

TMEM91 vs LENG8 — LARGE_INTESTINE

Explore this scatter interactively →