TMEM8B

Across TCGA patient cohorts, TMEM8B RNA expression is significantly associated with the RNA expression of many other genes, with 19,120 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TMEM8B-associated genes across cancer lineages are TESK1, EVI5L, and MED22. Each is linked with TMEM8B in more than 31 cancer types. Because this analysis shows association rather than direction, both TMEM8B-to-partner and partner-to-TMEM8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM8B versus TESK1 in ACC, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM8B→partner) and Y-score (partner→TMEM8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	TESK1 →	+1.101	+0.950	<.001	<.001	3	32
SCLC	EVI5L →	+1.325	+1.720	<.001	<.001	3	31
ACC	MED22 →	+1.007	+0.917	<.001	<.001	3	31
SCLC	ZER1 →	+1.145	+1.713	<.001	<.001	3	31
KIRP	SH2B1 →	+0.747	+0.858	<.001	<.001	3	31
SCLC	VMAC →	+0.832	+0.896	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,120 associations by consensus.

TMEM8B vs TESK1 — ACC

Explore this scatter interactively →