Across TCGA cell cohorts, TMEM89 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,912 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM89-associated GO terms across cancer lineages are Regulation of protein localization to chromatin, Cellular response to hexose stimulus, and Positive regulation of protein localization to chromatin. Each is linked with TMEM89 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM89-to-partner and partner-to-TMEM89 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM89→partner) and Y-score (partner→TMEM89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of protein localization to chromatin →	+0.095	+0.126	.001	.002	3	7
LIVER	Cellular response to hexose stimulus →	+0.066	+0.182	.009	.002	3	6
URINARY_TRACT	Positive regulation of protein localization to chromatin →	+0.091	+0.128	.001	<.001	3	6
URINARY_TRACT	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.093	+0.143	.001	<.001	3	6
BLOOD_Leukemia	Aromatic amino acid family catabolic process →	-0.222	-0.122	.002	.002	3	6
LIVER	Cellular response to carbohydrate stimulus →	+0.092	+0.210	.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,912 associations by consensus.

Exploration

TMEM89 survival (RNA) · tumor vs normal (RNA) · all TMEM89 data types