TMEM88

Across TCGA patient cohorts, TMEM88 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,559 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMEM88-associated proteins across cancer lineages are VWF, CAVIN2, and LAMB2. Each is linked with TMEM88 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM88-to-partner and partner-to-TMEM88 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM88 versus VWF in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM88→partner) and Y-score (partner→TMEM88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VWF →	+0.533	+0.667	<.001	<.001	3	8
BRCA	CAVIN2 →	+1.062	+0.980	<.001	<.001	3	8
HNSC	LAMB2 →	+0.760	+0.754	<.001	<.001	3	7
CCRCC	RPS2 →	-0.259	-1.029	<.001	<.001	3	7
BRCA	TMOD2 →	+0.435	+0.686	.001	.003	3	7
BRCA	TNS2 →	+0.533	+0.868	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,559 associations by consensus.

TMEM88 vs VWF — BRCA

Explore this scatter interactively →