TMEM88

Across TCGA cell cohorts, TMEM88 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,971 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM88-associated GO terms across cancer lineages are Response to fungicide, mRNA catabolic process, and Vacuole organization. Each is linked with TMEM88 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM88-to-partner and partner-to-TMEM88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to fungicide grouped by TMEM88-low versus TMEM88-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM88→partner) and Y-score (partner→TMEM88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to fungicide →	+0.183	+0.544	<.001	.009	3	9
BLOOD_Lymphoma	mRNA catabolic process →	+0.038	+0.650	<.001	<.001	3	8
STOMACH	Vacuole organization →	+0.070	+0.593	<.001	<.001	3	8
CNS	Viral transcription →	+0.067	+0.311	.002	.007	3	8
STOMACH	Regulation of proteasomal protein catabolic process →	+0.066	+0.505	.003	.006	3	8
STOMACH	Regulation of TORC1 signaling →	+0.074	+0.671	.003	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,971 associations by consensus.

Response to fungicide by TMEM88 expression — URINARY_TRACT

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