TMEM88

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM88 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM88-associated genes across cancer lineages are ARSH. Each is linked with TMEM88 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM88-to-partner and partner-to-TMEM88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARSH grouped by TMEM88-low versus TMEM88-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM88→partner) and Y-score (partner→TMEM88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaARSH →+0.012+4.922<.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

ARSH by TMEM88 expression — BLOOD_Leukemia

Box plot of ARSH in TMEM88-low vs TMEM88-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration