TMEM86A

Across TCGA cell cohorts, TMEM86A protein abundance is significantly associated with the RNA expression of many other genes, with 4,400 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM86A-associated genes across cancer lineages are AHNAK, DRAP1, and NMT2. Each is linked with TMEM86A in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM86A-to-partner and partner-to-TMEM86A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM86A versus AHNAK in BLOOD_Lymphoma, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM86A→partner) and Y-score (partner→TMEM86A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AHNAK →	+5.016	+2.098	<.001	<.001	3	14
BONE	DRAP1 →	+1.898	+3.415	.001	<.001	3	11
BONE	NMT2 →	+2.050	+2.649	.002	.003	3	10
BONE	SDC4 →	+3.812	+3.590	<.001	<.001	3	10
BONE	CCN1 →	+5.979	+3.222	<.001	.001	2	10
BONE	ITGA3 →	+5.470	+2.567	<.001	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,400 associations by consensus.

TMEM86A vs AHNAK — BLOOD_Lymphoma

Explore this scatter interactively →