TMEM86A

Across TCGA cell cohorts, TMEM86A protein abundance is significantly associated with the go_rna of many other GO terms, with 2,543 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM86A-associated GO terms across cancer lineages are Regulation of plasma membrane repair, Positive regulation of plasma membrane repair, and Protein dephosphorylation. Each is linked with TMEM86A in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM86A-to-partner and partner-to-TMEM86A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasma membrane repair grouped by TMEM86A-low versus TMEM86A-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM86A→partner) and Y-score (partner→TMEM86A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of plasma membrane repair →	+0.370	+1.652	.002	.007	3	12
BONE	Positive regulation of plasma membrane repair →	+0.331	+3.510	<.001	<.001	3	12
BONE	Protein dephosphorylation →	+0.076	+3.160	.003	<.001	3	8
CNS	Regulation of potassium ion transport →	+0.144	+0.995	.007	.002	3	8
BONE	Positive regulation of stress fiber assembly →	+0.255	+2.937	<.001	<.001	3	7
OVARY	Membrane raft assembly →	+0.247	+2.543	.002	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,543 associations by consensus.

Regulation of plasma membrane repair by TMEM86A expression — BLOOD_Lymphoma

Explore this box plot interactively →