TMEM75

Across TCGA patient cohorts, TMEM75 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,786 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM75-associated proteins across cancer lineages are GRWD1, PES1, and WDR36. Each is linked with TMEM75 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM75-to-partner and partner-to-TMEM75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM75 versus GRWD1 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM75→partner) and Y-score (partner→TMEM75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GRWD1 →	+0.349	+0.854	<.001	<.001	3	5
LSCC	PES1 →	+0.342	+0.628	<.001	<.001	3	5
LSCC	WDR36 →	+0.264	+0.673	<.001	<.001	3	5
LSCC	WDR75 →	+0.340	+0.685	<.001	<.001	3	5
LSCC	UTP6 →	+0.288	+0.504	<.001	<.001	3	5
LSCC	TBL3 →	+0.234	+0.581	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,786 associations by consensus.

TMEM75 vs GRWD1 — GBM

Explore this scatter interactively →