Across TCGA patient cohorts, TMEM72 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,964 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM72-associated proteins across cancer lineages are MDM1_T515, PBLD, and LGALS9. Each is linked with TMEM72 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM72-to-partner and partner-to-TMEM72 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM72→partner) and Y-score (partner→TMEM72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MDM1_T515 →	+0.442	+1.815	<.001	<.001	3	5
PDAC	PBLD →	+0.579	+0.251	<.001	<.001	3	5
HNSC	LGALS9 →	+0.509	+0.215	<.001	.001	3	5
CCRCC	MXRA5 →	-0.562	-0.898	.002	.001	3	4
CCRCC	NOSTRIN →	+0.693	+1.900	<.001	<.001	3	4
GBM	P3H1 →	-0.492	-0.384	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,964 associations by consensus.

Exploration

TMEM72 survival (RNA) · tumor vs normal (RNA) · all TMEM72 data types