Across TCGA patient cohorts, TMEM72 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM72-associated genes across cancer lineages are CMP, MPP, and aDC. Each is linked with TMEM72 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM72-to-partner and partner-to-TMEM72 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM72→partner) and Y-score (partner→TMEM72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CMP →	+0.033	+2.730	<.001	.027	3	1
LUSC	MPP →	+0.014	+3.694	<.001	.005	3	1
UCEC	aDC →	+0.077	+3.008	.031	.019	3	1
UCEC	Mesangial cells →	-0.061	-3.258	.001	.010	3	1
UCEC	Basophils →	+0.169	+3.584	.039	.003	3	1
UCEC	pDC →	+0.065	+3.008	.005	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

TMEM72 survival (RNA) · tumor vs normal (RNA) · all TMEM72 data types