Across TCGA cell cohorts, TMEM72 RNA expression is significantly associated with the go_rna of many other GO terms, with 989 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM72-associated GO terms across cancer lineages are Negative regulation of ribosome biogenesis, Regulation of protein localization to cilium, and Protein transmembrane transport. Each is linked with TMEM72 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM72-to-partner and partner-to-TMEM72 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM72→partner) and Y-score (partner→TMEM72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of ribosome biogenesis →	+0.253	+0.506	<.001	<.001	3	4
LUNG_NSCLC_LUSC	Regulation of protein localization to cilium →	+0.112	+0.020	<.001	.007	3	3
OVARY	Protein transmembrane transport →	+0.032	+0.080	.001	.009	3	3
BONE	Regulation of pigmentation →	+0.081	+0.361	<.001	.001	3	3
BONE	Negative regulation of mRNA catabolic process →	+0.068	+0.460	<.001	.001	3	3
BONE	Regulation of protein localization to ciliary membrane →	+0.080	+0.358	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 989 associations by consensus.

Exploration

TMEM72 survival (RNA) · tumor vs normal (RNA) · all TMEM72 data types