TMEM68

Across TCGA patient cohorts, TMEM68 protein abundance is significantly associated with the RNA expression of many other genes, with 4,908 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM68-associated genes across cancer lineages are ARHGAP9, TGS1, and PCMTD1. Each is linked with TMEM68 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM68-to-partner and partner-to-TMEM68 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM68 versus ARHGAP9 in HNSC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM68→partner) and Y-score (partner→TMEM68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARHGAP9 →	-0.803	-0.286	<.001	<.001	3	4
LSCC	TGS1 →	+0.570	+0.309	<.001	<.001	3	4
OV	PCMTD1 →	+0.526	+0.445	.001	<.001	3	4
OV	YTHDF3 →	+0.618	+0.403	<.001	.001	3	4
HNSC	TCEA1 →	+0.554	+0.261	.004	.003	3	4
OV	ARFGEF1 →	+0.636	+0.391	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,908 associations by consensus.

TMEM68 vs ARHGAP9 — HNSC

Explore this scatter interactively →