TMEM63C

Across TCGA patient cohorts, TMEM63C RNA expression is significantly associated with the protein abundance of many other proteins, with 20,000 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM63C-associated proteins across cancer lineages are ISG20, NFKB2, and PLCG2. Each is linked with TMEM63C in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM63C-to-partner and partner-to-TMEM63C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM63C versus ISG20 in LSCC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63C→partner) and Y-score (partner→TMEM63C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ISG20 →	-0.516	-0.611	<.001	<.001	3	5
GBM	NFKB2 →	-0.313	-0.635	<.001	<.001	3	5
LSCC	PLCG2 →	-0.517	-0.604	<.001	<.001	3	5
BRCA	TNFAIP3 →	-0.519	-1.577	<.001	<.001	3	4
BRCA	PRODH →	+0.576	+0.975	.001	<.001	3	4
LSCC	DNAJC1 →	-0.388	-0.630	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,000 associations by consensus.

TMEM63C vs ISG20 — LSCC

Explore this scatter interactively →