TMEM63C

Across TCGA patient cohorts, TMEM63C protein abundance is significantly associated with the RNA expression of many other genes, with 2,767 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM63C-associated genes across cancer lineages are SLC22A18, PPP1R1A, and ANKS1B. Each is linked with TMEM63C in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM63C-to-partner and partner-to-TMEM63C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM63C versus SLC22A18 in BRCA, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63C→partner) and Y-score (partner→TMEM63C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC22A18 →	+0.747	+0.518	.005	.001	3	2
GBM	PPP1R1A →	+0.490	+0.337	.007	.002	3	2
GBM	ANKS1B →	+1.143	+0.446	.001	<.001	3	2
LUAD	TTC24 →	-0.389	-0.910	.001	.004	3	2
LUAD	RPL7P39 →	+1.087	+1.198	.005	.004	3	2
BRCA	SPTLC2 →	+0.569	+0.517	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,767 associations by consensus.

TMEM63C vs SLC22A18 — BRCA

Explore this scatter interactively →