TMEM63C

Across TCGA cell cohorts, TMEM63C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,016 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMEM63C-associated GO terms across cancer lineages are ATP biosynthetic process, Nucleoside triphosphate biosynthetic process, and Regulation of proteasomal protein catabolic process. Each is linked with TMEM63C in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM63C-to-partner and partner-to-TMEM63C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by TMEM63C-low versus TMEM63C-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63C→partner) and Y-score (partner→TMEM63C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ATP biosynthetic process →	+0.064	+0.877	.001	.001	3	12
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.133	+1.248	.003	.004	3	12
STOMACH	Regulation of proteasomal protein catabolic process →	+0.062	+0.957	<.001	.002	3	11
OESOPHAGUS	Purine ribonucleoside triphosphate metabolic process →	+0.125	+1.416	<.001	.001	3	11
OVARY	ATP synthesis coupled electron transport →	+0.090	+1.338	.003	<.001	3	11
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.090	+1.338	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,016 associations by consensus.

ATP biosynthetic process by TMEM63C expression — OVARY

Explore this box plot interactively →