TMEM60

Across TCGA patient cohorts, TMEM60 protein abundance is significantly associated with the RNA expression of many other genes, with 3,765 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM60-associated genes across cancer lineages are WBP11P2, KDM4B, and TSSK4. Each is linked with TMEM60 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM60-to-partner and partner-to-TMEM60 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM60 versus WBP11P2 in CCRCC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM60→partner) and Y-score (partner→TMEM60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	WBP11P2 →	-0.120	-0.739	.003	.003	3	3
LUAD	KDM4B →	-0.394	-0.897	<.001	<.001	3	3
GBM	TSSK4 →	-0.445	-0.401	<.001	.001	3	3
LUAD	PRR14 →	-0.411	-0.801	<.001	<.001	3	3
LUAD	IPO9-AS1 →	-0.402	-0.846	.002	<.001	3	3
GBM	PRKACA →	-0.488	-0.505	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,765 associations by consensus.

TMEM60 vs WBP11P2 — CCRCC

Explore this scatter interactively →