TMEM51

Across TCGA patient cohorts, TMEM51 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,042 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM51-associated proteins across cancer lineages are EFHD2, NADK, and CASP4. Each is linked with TMEM51 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM51-to-partner and partner-to-TMEM51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM51 versus EFHD2 in OV, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM51→partner) and Y-score (partner→TMEM51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EFHD2 →	+0.399	+0.701	.003	.001	3	7
BRCA	NADK →	+0.418	+0.737	<.001	<.001	3	7
GBM	CASP4 →	+0.441	+0.564	.003	.002	3	6
OV	MRPL40 →	-0.432	-0.570	<.001	.003	3	5
LSCC	GBP2 →	+0.445	+0.467	<.001	.001	3	5
LSCC	TMEM51_S115 →	+0.918	+0.581	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,042 associations by consensus.

TMEM51 vs EFHD2 — OV

Explore this scatter interactively →