TMEM51

Across TCGA cell cohorts, TMEM51 RNA expression is significantly associated with the RNA expression of many other genes, with 8,252 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM51-associated genes across cancer lineages are EFHD2, THEMIS2, and NABP1. Each is linked with TMEM51 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM51-to-partner and partner-to-TMEM51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM51 versus EFHD2 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM51→partner) and Y-score (partner→TMEM51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	EFHD2 →	+1.810	+1.434	<.001	<.001	3	9
PANCREAS	THEMIS2 →	+1.846	+1.596	<.001	<.001	3	9
LUNG_NSCLC_LUSC	NABP1 →	+2.232	+1.948	.002	<.001	3	8
LUNG_NSCLC_LUSC	PLEKHN1 →	+1.735	+1.961	<.001	<.001	3	8
LUNG_NSCLC_LUSC	RER1 →	+1.105	+1.643	.004	<.001	3	8
LUNG_NSCLC_LUSC	MICAL2 →	+4.105	+1.617	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,252 associations by consensus.

TMEM51 vs EFHD2 — LUNG_NSCLC_LUSC

Explore this scatter interactively →