TMEM47

Across TCGA patient cohorts, TMEM47 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM47-associated proteins across cancer lineages are TAGLN, PDLIM5, and CNN3. Each is linked with TMEM47 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM47-to-partner and partner-to-TMEM47 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM47 versus TAGLN in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM47→partner) and Y-score (partner→TMEM47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TAGLN →	+0.831	+0.960	<.001	<.001	3	9
UCEC	PDLIM5 →	+0.577	+1.137	<.001	<.001	3	9
OV	CNN3 →	+0.662	+1.074	.002	.004	3	9
BRCA	THBS3 →	+0.661	+1.381	<.001	<.001	3	8
UCEC	TLN1_S1641 →	+1.162	+1.086	<.001	.005	3	8
HNSC	TPM1 →	+0.614	+0.788	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,938 associations by consensus.

TMEM47 vs TAGLN — BRCA

Explore this scatter interactively →