TMEM47

Across TCGA patient cohorts, TMEM47 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,295 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM47-associated proteins across cancer lineages are SCO1, INPP5F_S940, and MIPEP. Each is linked with TMEM47 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM47-to-partner and partner-to-TMEM47 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM47 versus SCO1 in UCEC, with a Pearson correlation of 0.80.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM47→partner) and Y-score (partner→TMEM47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SCO1 →	+0.790	+1.044	<.001	<.001	3	2
GBM	INPP5F_S940 →	-1.032	-0.867	<.001	<.001	3	2
UCEC	MIPEP →	+0.408	+0.851	<.001	<.001	3	2
UCEC	PCNX3_S1955 →	+0.519	+0.792	.003	.004	3	2
GBM	PHKB →	+0.542	+0.884	<.001	<.001	3	2
UCEC	FUNDC1 →	+0.435	+0.812	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,295 associations by consensus.

TMEM47 vs SCO1 — UCEC

Explore this scatter interactively →