TMEM47

Across TCGA cell cohorts, TMEM47 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,293 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM47-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, and Neuroligin clustering involved in postsynaptic membrane assembly. Each is linked with TMEM47 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM47-to-partner and partner-to-TMEM47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by TMEM47-low versus TMEM47-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM47→partner) and Y-score (partner→TMEM47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.060	+1.484	.004	.005	3	8
SKIN	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.060	+1.658	<.001	.004	3	7
BREAST	Neuroligin clustering involved in postsynaptic membrane assembly →	+1.216	+1.531	<.001	.003	3	7
CNS	Amyloid-beta clearance by transcytosis →	+0.120	+2.566	<.001	<.001	3	7
KIDNEY	Outflow tract septum morphogenesis →	+0.161	+1.414	<.001	<.001	3	6
LIVER	Cytosolic ribosome assembly →	+0.090	+2.959	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,293 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by TMEM47 expression — KIDNEY

Explore this box plot interactively →