TMEM43

Across TCGA patient cohorts, TMEM43 protein abundance is significantly associated with the RNA expression of many other genes, with 14,802 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM43-associated genes across cancer lineages are CRTAP, DAPK3, and FN1. Each is linked with TMEM43 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM43-to-partner and partner-to-TMEM43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM43 versus CRTAP in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM43→partner) and Y-score (partner→TMEM43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRTAP →	+0.494	+0.238	<.001	<.001	3	6
OV	DAPK3 →	+0.621	+0.265	.001	.009	3	6
OV	FN1 →	+2.555	+0.423	<.001	<.001	3	5
OV	COL8A1 →	+2.449	+0.440	<.001	<.001	3	5
OV	PDPN →	+1.446	+0.400	<.001	<.001	3	5
OV	VIM →	+1.062	+0.383	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,802 associations by consensus.

TMEM43 vs CRTAP — LSCC

Explore this scatter interactively →