TMEM41A

Across TCGA patient cohorts, TMEM41A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,046 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM41A-associated proteins across cancer lineages are FXR1, EIF4G1, and ABCF3. Each is linked with TMEM41A in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM41A-to-partner and partner-to-TMEM41A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM41A versus FXR1 in LSCC, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM41A→partner) and Y-score (partner→TMEM41A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FXR1 →	+0.421	+0.768	<.001	<.001	3	8
LSCC	EIF4G1 →	+0.342	+0.884	<.001	<.001	3	8
LSCC	ABCF3 →	+0.395	+0.860	<.001	<.001	3	7
LSCC	POLR2H →	+0.353	+0.750	<.001	<.001	3	6
LSCC	OPA1 →	+0.460	+0.697	<.001	<.001	3	6
HNSC	SENP2_S344 →	+0.643	+0.932	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,046 associations by consensus.

TMEM41A vs FXR1 — LSCC

Explore this scatter interactively →