TMEM41A

Across TCGA patient cohorts, TMEM41A protein abundance is significantly associated with the RNA expression of many other genes, with 11,134 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM41A-associated genes across cancer lineages are NCAPH, DVL3, and POLR2H. Each is linked with TMEM41A in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM41A-to-partner and partner-to-TMEM41A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM41A versus NCAPH in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM41A→partner) and Y-score (partner→TMEM41A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NCAPH →	+0.773	+0.415	<.001	.001	3	5
LSCC	DVL3 →	+0.882	+0.376	<.001	<.001	3	5
LSCC	POLR2H →	+0.899	+0.463	<.001	<.001	3	5
HNSC	NEMP1 →	+0.764	+0.306	<.001	<.001	3	5
LSCC	ALG3 →	+0.837	+0.467	<.001	<.001	3	5
LSCC	EEF1AKMT4 →	+1.006	+0.460	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,134 associations by consensus.

TMEM41A vs NCAPH — LSCC

Explore this scatter interactively →