TMEM41A

Across TCGA cell cohorts, TMEM41A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,427 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM41A-associated GO terms across cancer lineages are Maintenance of centrosome location, Phospholipid biosynthetic process, and Glycerophospholipid metabolic process. Each is linked with TMEM41A in more than 10 cancer types. Because this analysis shows association rather than direction, both TMEM41A-to-partner and partner-to-TMEM41A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of centrosome location grouped by TMEM41A-low versus TMEM41A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM41A→partner) and Y-score (partner→TMEM41A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Maintenance of centrosome location →	+0.139	+0.785	.003	.001	3	11
URINARY_TRACT	Phospholipid biosynthetic process →	+0.042	+0.547	<.001	.001	3	10
LUNG_NSCLC_LUAD	Glycerophospholipid metabolic process →	+0.038	+0.707	<.001	<.001	3	10
URINARY_TRACT	Glycerophospholipid biosynthetic process →	+0.040	+0.518	.002	.003	3	10
LIVER	Protein targeting to ER →	+0.105	+0.824	<.001	<.001	3	9
CNS	Regulation of post-translational protein modification →	+0.049	+0.549	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,427 associations by consensus.

Maintenance of centrosome location by TMEM41A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →