TMEM31

Across TCGA cell cohorts, TMEM31 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,255 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM31-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with TMEM31 in more than 10 cancer types. Because this analysis shows association rather than direction, both TMEM31-to-partner and partner-to-TMEM31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TMEM31-low versus TMEM31-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM31→partner) and Y-score (partner→TMEM31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of myoblast fusion →	+0.085	+0.250	<.001	<.001	3	11
OVARY	Regulation of myoblast fusion →	+0.079	+0.213	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.084	+0.232	<.001	<.001	3	9
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.076	+0.194	<.001	.001	3	9
BREAST	ATP biosynthetic process →	+0.077	+0.354	.001	.002	3	8
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.082	+0.588	<.001	.003	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,255 associations by consensus.

Negative regulation of myoblast fusion by TMEM31 expression — SOFT_TISSUE

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