TMEM30BP1

Across TCGA pan-cancer cohorts, TMEM30BP1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TMEM30BP1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher TMEM30BP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TMEM30BP1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and THYM show a favorable association.

KICH, KIRC, and LGG are the cancer types where TMEM30BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	II,III,IV	0.393	0.928	.003	58	view →
KIRC	DFS	Tertile	All	0.511	0.687	<.001	53	view →
LGG	OS	Median	All	0.336	0.552	<.001	53	view →
KIRP	DFS	Quartile	II,III,IV	0.143	0.940	.001	49	view →
THCA	DFS	Quartile	II,III,IV	0.587	0.935	.004	41	view →
ACC	DFS	Quartile	IV	0.053	0.579	.006	31	view →
GBM	DFS	Quartile	All	0.152	0.425	.005	24	view →
SKCM	DFS	Quartile	All	0.288	0.152	.007	22	view →
STAD	DFS	Quartile	II,III,IV	0.346	0.567	.012	21	view →
LAML	DFS	Quartile	All	0.400	0.754	.004	14	view →
MESO	OS	Tertile	IV	0.189	0.684	.007	12	view →
READ	OS	Tertile	IV	0.587	1.000	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TMEM30BP1–KICH (DFS)

Open the KICH breakdown →