Across TCGA patient cohorts, TMEM273 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,423 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM273-associated proteins across cancer lineages are ARHGAP45, ARHGAP9, and RCSD1. Each is linked with TMEM273 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM273-to-partner and partner-to-TMEM273 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM273→partner) and Y-score (partner→TMEM273) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARHGAP45 →	+0.587	+0.917	<.001	<.001	3	10
OV	ARHGAP9 →	+0.480	+1.117	<.001	<.001	3	10
HNSC	RCSD1 →	+0.698	+0.907	<.001	<.001	3	10
HNSC	RIN3 →	+0.565	+1.169	<.001	<.001	3	10
HNSC	LCP2 →	+0.591	+0.749	<.001	<.001	3	10
LSCC	STK10 →	+0.473	+0.912	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,423 associations by consensus.

Exploration

TMEM273 survival (RNA) · tumor vs normal (RNA) · all TMEM273 data types