TMEM273

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM273 mutation is significantly associated with the RNA expression of many other genes, with 2,232 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM273-associated genes across cancer lineages are COX5BP8, OR51C4P, and MIR6765. Each is linked with TMEM273 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM273-to-partner and partner-to-TMEM273 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM273→partner) and Y-score (partner→TMEM273) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCOX5BP8 →+0.192+4.893.005.00533
CESCOR51C4P →+0.039+7.584<.001<.00132
CESCMIR6765 →+0.418+5.201<.001.00732
LUSCRNA5-8SN1 →+0.189+5.578.004<.00132
LUADRNU6-1126P →+0.260+4.859<.001.00432
LUADRN7SKP121 →+0.099+4.612<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,232 associations by consensus.

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