Across TCGA cell cohorts, TMEM273 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,814 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM273-associated GO terms across cancer lineages are Negative regulation of cell-cell adhesion, Positive regulation of intracellular transport, and Regulation of focal adhesion assembly. Each is linked with TMEM273 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM273-to-partner and partner-to-TMEM273 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM273→partner) and Y-score (partner→TMEM273) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of cell-cell adhesion →	+0.053	+0.037	.003	.007	2	7
CNS	Positive regulation of intracellular transport →	+0.054	+0.743	<.001	.008	2	7
BLOOD_Leukemia	Regulation of focal adhesion assembly →	+0.063	+2.325	<.001	<.001	3	6
BLOOD_Leukemia	Regulation of cell-substrate junction assembly →	+0.063	+2.325	<.001	<.001	3	6
OVARY	Nucleoside triphosphate metabolic process →	+0.057	+0.732	.005	.003	3	6
BLOOD_Leukemia	Endosome transport via multivesicular body sorting pathway →	+0.061	+2.209	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,814 associations by consensus.

Exploration

TMEM273 survival (RNA) · tumor vs normal (RNA) · all TMEM273 data types