TMEM269

Across TCGA patient cohorts, TMEM269 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,507 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM269-associated proteins across cancer lineages are MED24, NIPBL, and PAXBP1. Each is linked with TMEM269 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM269-to-partner and partner-to-TMEM269 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM269 versus MED24 in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM269→partner) and Y-score (partner→TMEM269) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MED24 →	+0.208	+0.318	.003	.005	3	5
GBM	NIPBL →	+0.275	+0.354	<.001	<.001	3	4
GBM	PAXBP1 →	+0.250	+0.342	<.001	<.001	3	4
LSCC	SPIN1 →	+0.276	+0.279	.001	<.001	3	4
GBM	SRSF3 →	+0.348	+0.449	<.001	<.001	3	4
LSCC	ZMYM3 →	+0.366	+0.314	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,507 associations by consensus.

TMEM269 vs MED24 — UCEC

Explore this scatter interactively →